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Who needs insulin? UT Southwestern study shows that without glucagon, insulin may not be that important. |
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UT Southwestern: The study used mice specially bred not to respond to glucagon. Then the researchers killed about 90 percent of the mice’s insulin-producing ability, but provided no other medication. Nonetheless, the mice continued to thrive, showing no diabetes symptoms. Even when the mice were fed large doses of glucose, the amount of sugar in their blood stayed normal.
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Rockwell to launch phase 3 studies of iron-fortified dialysate. |
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Nephronline: Renal biopharmaceutical company Rockwell Medical Inc. announced that the clinical research divisions of the two largest dialysis companies in North America have signed agreements to participate in the company's pivotal Phase 3 CRUISE studies using Soluble Ferric Pyrophosphate (SFP) as a continuous iron replacement therapeutic.
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Circadian rhythms demonstrable even in red blood cells. |
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EurekAlert: One study, from the University of Cambridge's Institute of Metabolic Science, has for the first time identified 24-hour rhythms in red blood cells. This is significant because circadian rhythms have always been assumed to be linked to DNA and gene activity, but – unlike most of the other cells in the body – red blood cells do not have DNA.
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NEJM: rTPA use lowers risk on infection and sepsis in dialysis patients with CVCs. |
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NEJM: Dr. Brenda Hemmelgarn from the University of Calgary Faculty of Medicine and her colleague Dr. Nairne Scott-Douglas, both members of the Libin Cardiovascular Institute of Alberta, undertook a randomized trial at 11 sites across Canada. 115 hemodialysis patients were administered the usual catheter locking solution of heparin after every dialysis session, while 110 patients received rt-PA once a week. Researchers found that those receiving only heparin were twice as likely to suffer a catheter malfunction and were at an almost three-fold increased risk of blood stream infection.
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Could the predilection for autoimmune diseases among women be due to avoidance of dirt? |
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Oregon State U: “What I am proposing is new ways of looking at old studies,” she said. “The hygiene hypothesis is well-supported, but what I am hoping is that the epidemiologists and clinicians go back and examine their data through the lens of gender.”
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