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Rockwell proceeding with Phase III trial of dialysate-added iron. |
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Globe Newswire: Rockwell Medical ... announced today that it has commenced enrollment in its pivotal Phase III CRUISE-1 clinical study, designed to treat iron deficiency anemia in hemodialysis dependent-chronic kidney disease patients receiving erythropoietin.
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Ok, you know about FGF23. But FGF19 may be even more important in glucose metabolism. |
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EurekAlert: Another hormone, fibroblast growth factor 19 (FGF19), has insulin-like characteristics beyond its role in bile acid synthesis. Unlike insulin, however, FGF19 does not cause excess glucose to turn to fat, suggesting that its activation could lead to new treatments for diabetes or obesity. "The fundamental discovery is that there is a pathway that exists that is required for the body, after a meal, to store glucose in the liver and drive protein synthesis. That pathway is independent of insulin," said Dr. David Mangelsdorf, chairman of pharmacology at UT Southwestern.
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Do you still ask about green or yellow phlegm in your patients who are coughing? |
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EurekAlert: The research found that patients producing discoloured phlegm are prescribed antibiotics more frequently than those not producing phlegm unlike those producing clear/white phlegm. Crucially, antibiotic treatment was not associated with greater rate or magnitude of symptoms score resolution among those who produced yellow or green phlegm. Neither was recovery among those feeling generally unwell on its own, or taken together with phlegm production, associated with antibiotic treatment. Clinicians and patients are therefore likely to both be over interpreting the importance of the colour of phlegm in the decision whether or not to prescribe, or take, antibiotics.
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Multidrug-resistant Klebsiella pneumonia found in Los Angeles County area acute care hospitals. |
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EurekAlert: After declaring CRKP a laboratory-reportable disease, meaning that its appearance must be reported by a laboratory if found during testing, Terashita's team noted unexpectedly high numbers of CRKP across the county. During the study period of June 2010 to December 2010, 350 cases of CRKP were identified. Many of the cases, 42 percent, occurred in long-term acute care hospitals, and 6 percent were found in patients residing in skilled nursing facilities.
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Extended dosing of darbepoetin alfa in peritoneal dialysis patients - 7thSpace Interactive (press release) |
7thSpace Interactive (press release)
Anemia is common among peritoneal dialysis (PD) patients, and most patients require erythropoiesis-stimulating agents (ESA) to maintain their hemoglobin concentrations within current guideline recommendations. Darbepoetin alfa is an ESA with a 3-fold
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