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Egg freezing works to preserve fertility. |
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Boston.com: Here’s good news for women who are thinking about freezing eggs from their ovaries because they’re not ready to have a baby -- and are worried that they’ll be too old when they are -- or are undergoing chemotherapy or radiation that might render them infertile. The technique really does work to achieve successful pregnancies and should no longer be considered experimental, according to new guidelines set to be issued Monday by the American Society for Reproductive Medicine.
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Vitamin D supplements may benefit lupus patients |
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EurekAlert: In a prospective clinical trial, Nathalie Costedoat-Chalumeau and colleagues set out to evaluate the safety and immunological effects of vitamin D supplementation in 20 SLE patients with low vitamin D levels. They observed these patients over six months and found that vitamin D was not only well-tolerated but, more importantly, there were no SLE flare-ups during the follow-up period. Vitamin D supplementation in these patients caused an increase in beneficial CD4+ cells (mature Th cells), an increase in Treg cells and a decrease of effector Th1 and Th17 cells. It also induced a decrease of memory B cell and anti-DNA antibodies – all beneficial for SLE symptoms. The authors found that no modification of existing immunosuppressant drugs was needed, nor any new drugs initiated.
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Kidney grafts function longer in Europe than in the United States. |
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University of Heidelberg: Kidney transplants performed in Europe are considerably more successful in the long run than those performed in the United States. While the one-year survival rate is 90% in both Europe and the United States, after five years, 77% of the donor kidneys in Europe still function, while in the United States, this rate among white Americans is only 71%. After ten years, graft survival for the two groups is 56% versus 46%, respectively. The lower survival rates compared to Europe also apply to Hispanic Americans, in whom 48% of the transplanted kidneys still function after ten years, and particularly to African Americans, whose graft survival is a mere 33%.
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Lower chloride use in intravenous fluids may reduce risk of acute kidney injury. |
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EurekAlert: "The findings of this study show that a chloride-restrictive intravenous strategy is associated with a decrease in the incidence of the more severe stages of AKI and the use of RRT. These findings, together with the previously reported observations that a chloride-liberal intravenous strategy can be associated with higher cost, and the easy availability of cheap alternatives suggest the need to exert prudence in the administration of fluids with supraphysiological concentrations of chloride, especially in critically ill patients with evidence of early acute renal dysfunction or at risk of acute dysfunction," the researchers write. "Our findings need to be confirmed in different health care systems and different ICUs."
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Cranberry juice unlikely to help in cystitis. |
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EurekAlert: In the current review, the researchers gathered together evidence from 24 studies that involved a total of 4,473 people. These studies included 14 added since the 2008 update. Those in treatment groups were given cranberry juice, tablets or capsules, while those in control groups were given placebo cranberry products, water, methenamine hippurate, antibiotics, lactobacillus or nothing. Although in some studies there were small benefits for women suffering from recurring infections, women would have to consume two glasses of cranberry juice per day for long periods to prevent one infection. The researchers conclude that current evidence does not support cranberry juice as a means of preventing UTIs.
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