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Rare gene deletion that protects the obses against type 2 diabetes identified. |
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NY Times: A new study based on genetic testing of 150,000 people has found a rare mutation that protects even fat people from getting Type 2 diabetes. The effect is so pronounced — the mutation reduces risk by two-thirds — that it provides a promising new target for developing a drug to mimic the mutation’s effect.
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Beta-blockade found to benefit ESRD patient survival and CV risk |
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ERA-EDTA: Rajiv Agarwal and colleagues report in the March issue of NDT the very first study to make a head-to-head comparison of a beta-blocker (atenolol) with an ACEi (lisinopril), the Hypertension in Haemodialysis Patients Treated with Atenolol or Lisinopril (HDPAL) study, a trial in which the primary endpoint was regression of LVH. This trial was recently presented at the 2013 ASN Congress in Atlanta. After a 12-month treatment period with atenolol or with lisinopril-based regimens, hypertensive patients achieved a similar fall in 44-h interdialysis ABPM (-21/-13 mmHg; -18/-10 mmHg, respectively). Nonetheless, the risk for hospitalizations for heart failure and cardiovascular events including myocardial infarction, stroke and cardiovascular death was markedly higher in the lisinopril than in the atenolol group. Overall, the incidence rate ratio for major cardiovascular events was more than double in the lisinopril than in the atenolol group, and the independent safety monitoring board recommended an early stop of the trial.
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New form of pneumococcal vaccine (Prevnar 13) protects elderly adults. |
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Reuters: Pfizer Inc said on Monday that Prevnar 13, its blockbuster vaccine against childhood infections, prevented pneumonia outside of hospitals in people age 65 and older, in one of the largest drug trials ever conducted.
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Open Biome (fecal material transplant company) FAQs |
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Open Biome: Clinician FAQs. We've assembled many of the common inquiries we receive from clinicians below. If you can't find the answer to your question, please email us at
This e-mail address is being protected from spambots. You need JavaScript enabled to view it
and we'd be happy to help.
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Fecal transplantation becoming more popular; a company offers collection service. |
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Live Science: Smith said he became interested in the topic when a family friend, frustrated with not being able to find a physician to provide a fecal transplant, got a donation and performed an enema on himself. For now, Smith has attempted one solution, by cofounding a stool bank near MIT, called OpenBiome.
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