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New genetic cause of primary hyperaldosteronism identified, and it's not rare. |
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EurekAlert: High blood pressure may in some cases be caused by benign hormone-producing tumours of the adrenal cortex. A joint Swedish-American research effort has now uncovered a genetic cause behind the occurrence of such tumours. The findings were published today in the journal Science. Approximately 5 per cent of patients with elevated blood pressure have benign endocrine tumours in their adrenal gland. The tumours produce abnormally high levels of the hormone aldosterone (the condition is known as primary aldosteronism), which in turn causes blood pressure to rise. Why the tumours arise has thus far been unknown.
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