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w e + w i l l + b e n e f i t + f r o m + t h e + a d d i t i o n + o f + h e m o s p h e r e % 2 7 s + e x i s t i n g + b u s i n e s s + t h i s + y e a r % 2 c + w e + a n t i c i p a t e + t h a t + o u r + s a l e s + f o r c e + w i l l + b e g i n + d r i v i n g + a + m e a n i n g f u l + a c c e l e r a t i o n + o f + h e r o + g r a f t + g r o w t h + b e g i n n i n g + i n + 2 0 1 3 % 2 2 % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a a s s u m i n g + t h e + t r a n s a c t i o n + c l o s e s + i n + m a y + a s + a n t i c i p a t e d % 2 c + t h e + c o m p a n y + e x p e c t s + r e v e n u e s + o f + b e t w e e n + % 2 4 2 5 + m i l l i o n + a n d + % 2 4 3 5 + m i l l i o n + f o r + t h e + h e m o s p h e r e + p r o d u c t + l i n e + i n + 2 0 1 2 + t h e + c o m p a n y + e x p e c t 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t + i n c o m e + t a x + r a t e + h o w e v e r % 2 c + d u e + t o + t h e + n o n - d e d u c t i b i l i t y + o f + c e r t a i n + t r a n s a c t i o n + e x p e n s e s % 2 c + t h e + c o m p a n y + e x p e c t s + i t s + i n c o m e + t a x + r a t e + i n + t h e + s e c o n d + q u a r t e r + o f + 2 0 1 2 + t o + b e + h i g h e r + t h a n + 3 5 + p e r c e n t % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a p r e s e n t a t i o n + s l i d e s % 2 c + c o n f e r e n c e + c a l l + a n d + w e b + c a s t % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a c r y o l i f e + w i l l + h o l d + a + t e l e c o n f e r e n c e + c a l l + a n d + l i v e + w e b c a s t + w i t h + a + s l i d e + p r e s e n t a t i o n + t o d a y + a t + 1 1 % 3 a 0 0 + a m + e a s t e r n + t i m e + % 2 8 e t % 2 9 + t o + d i s c u s s + t h e + t r a n s a c t i o n % 2 c + h o s t e d + b y + s t e v e n + g + a n d e r s o n % 2 c + p r e s i d e n t + a n d + c h i e f + e x e c u t i v e + o f f i c e r + o f + c r y o l i f e + t h e + c o n f e r e n c e + c a l l + w i l l + i n c l u d e + p r e s e n t a t i o n + s l i d e s + t h a t + w i l l + b e + p o s t e d + o n + t h e + c r y o l i f e + w e b s i t e + a t + + % 0 d % 0 a w w w c r y o l i f e c o m + + + + + t o + d o w n l o a d + a n d + v i e w + t h e + s l i d e + p r e s e n t a t i o n % 2 c + g o + t o + t h e + i n v e s t o r + r e l a t i o n s + s e c t i o n + o f + t h e + c r y o l i f e + w e b s i t e + t h e + p r e s e n t a t i o n + w i l l + b e + p o s t e d + u n d e r + t h e + w e b c a s t + l i n k + p r i o r + t o + t h e + s t a r t + o f + t h e + c o n f e r e n c e + c a l l % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a t o + l i s t e n + t o + t h e + l i v e + t e l e c o n f e r e n c e % 2 c + p l e a s e + d i a l + 2 0 1 - 6 8 9 - 8 2 6 1 + a + f e w + m i n u t e s + p r i o r + t o + 1 1 % 3 a 0 0 + a m + % 2 8 e t % 2 9 + a + r e p l a y + o f + t h e + t e l e c o n f e r e n c e + w i l l + b e + a v a i l a b l e + m a y + 1 5 + t h r o u g h + j u n e + 1 + a n d + c a n + b e + a c c e s s e d + b y + c a l l i n g + % 2 8 t o l l + f r e e % 2 9 + 8 7 7 - 6 6 0 - 6 8 5 3 + o r + 2 0 1 - 6 1 2 - 7 4 1 5 + t h e + a c c o u n t + n u m b e r + f o r + t h e + r e p l a y + i s + 2 4 4 + a n d + t h e + c o n f e r e n c e + n u m b e r + i s + 3 9 4 4 1 2 % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + 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m p a n y % 2 7 s + w e b s i t e + a t + + % 0 d % 0 a w w w h e m o s p h e r e c o m + + + + % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a a b o u t + c r y o l i f e % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a f o u n d e d + i n + 1 9 8 4 % 2 c + c r y o l i f e % 2 c + i n c + i s + a + l e a d e r + i n + t h e + p r o c e s s i n g + a n d + d i s t r i b u t i o n + o f + i m p l a n t a b l e + l i v i n g + h u m a n + t i s s u e s + f o r + u s e + i n + c a r d i a c + a n d + v a s c u l a r + s u r g e r i e s + t h r o u g h o u t + t h e + u s % 2 c + c e r t a i n + c o u n t r i e s + i n + e u r o p a % 2 c + a n d + c a n a d a + + c r y o l i f e % 2 7 s + c r y o v a l v e % c 3 % 8 2 % c 2 % a e + s g + p u l m o n a r y + h e a r t + v a l v e % 2 c + p r o c e s s e d + u s i n g + c r y o l i f e % 2 7 s + p r o p r i e t a r y + s y n e r g r a f t % c 3 % 8 2 % c 2 % a e + t e c h n o l o g y % 2 c + h a s + f d a + 5 1 0 % 2 8 k % 2 9 + c l e a r a n c e + f o r + t h e + r e p l a c e m e n t + o f + d i s e a s e d % 2 c + d a m a g e d % 2 c + m a l f o r m e d % 2 c + o r + m a l f u n c t i o n i n g + n a t i v e + o r + p r o s t h e t i c + p u l m o n a r y + v a l v e s + c r y o l i f e % 2 7 s + c r y o p a t c h % c 3 % 8 2 % c 2 % a e + s g + p u l m o n a r y + c a r d i a c + p a t c h + h a s + f d a + 5 1 0 % 2 8 k % 2 9 + c l e a r a n c e + f o r + t h e + r e p a i r + o r + r e c o n s t r u c t i o n + o f + t h e + r i g h t + v e n t r i c u l a r + o u t f l o w + t r a c t + % 2 8 r v o t % 2 9 % 2 c + w h i c h + i s + a + s u r g e r y + c o m m o n l y + p e r f o r m e d + i n + c h i l d r e n + w i t h + c o n g e n i t a l + h e a r t + d e f e c t s % 2 c + s u c h + a s + t e t r a l o g y + o f + f a l l o t % 2 c + t r u n c u s + a r t e r i o s u s % 2 c + a n d + p u l m o n a r y + a t r e s i a + + c r y o p a t c h + s g + i s + d i s t r i b u t e d + i n + t h r e e + a n a t o m i c + c o n f i g u r a t i o n s % 3 a + p u l m o n a r y + h e m i - a r t e r y % 2 c + p u l m o n a r y + t r u n k % 2 c + a n d + p u l m o n a r y + b r a n c h + c r y o l i f e % 2 7 s + b i o g l u e % c 3 % 8 2 % c 2 % a e + s u r g i c a l + a d h e s i v e + i s + f d a + a p p r o v e d + a s + a n + a d j u n c t + t o + s u t u r e s + a n d + s t a p l e s + f o r + u s e + i n + a d u l t + p a t i e n t s + i n + o p e n + s u r g i c a l + r e p a i r + o f + l a r g e + v e s s e l s + + b i o g l u e + i s + a l s o + c e + m a r k e d + i n + t h e + e u r o p e a n + c o m m u n i t y + f o r + u s e + i n + s o f t + t i s s u e + r e p a i r + a n d + w a s + r e c e n t l y + a p p r o v e d + i n + j a p a n + f o r + u s e + i n + t h e + r e p a i r + o f + a o r t i c + d i s s e c t i o n s + a d d i t i o n a l + m a r k e t i n g + a p p r o v a l s + f o r + b i o g l u e + h a v e + b e e n + g r a n t e d + i n + s e v e r a l + o t h e r + c o u n t r i e s + t h r o u g h o u t + t h e + w o r l d + c r y o l i f e % 2 c + t h r o u g h + i t s + s u b s i d i a r y + c a r d i o g e n e s i s + c o r p o r a t i o n % 2 c + s p e c i a l i z e s + i n + t h e + t r e a t m e n t + o f + c a r d i o v a s c u l a r + d i s e a s e + a n d + t h e + s a l e + o f + d e v i c e s + t h a t + t r e a t + s e v e r e + a n g i n a + + i t s + m a r k e t + l e a d i n g + f d a - a p p r o v e d + h o l m i u m % 3 a + y a g + l a s e r + s y s t e m + a n d + s i n g l e + u s e + f i b e r - o p t i c + d e l i v e r y + s y s t e m s + a r e + u s e d + t o + p e r f o r m + a + s u r g i c a l + p r o c e d u r e + k n o w n + a s + t r a n s m y o c a r d i a l + r e v a s c u l a r i z a t i o n + % 2 8 t m r % 2 9 + c r y o l i f e + d i s t r i b u t e s + p e r c l o t % c 3 % 8 2 % c 2 % a e % 2 c + a n + a b s o r b a b l e + p o w d e r + h e m o s t a t % 2 c + i n + t h e + e u r o p e a n + c o m m u n i t y + c r y o l i f e % 2 7 s + b i o f o a m % 2 8 t m % 2 9 + s u r g i c a l + m a t r i x + i s + c e + m a r k e d + i n + t h e + e u r o p e a n + c o m m u n i t y + f o r + u s e + a s + a n + a d j u n c t + i n + t h e + s e a l i n g + o f + a b d o m i n a l + p a r e n c h y m a l + t i s s u e s + % 2 8 l i v e r + a n d + s p l e e n % 2 9 + w h e n + c e s s a t i o n + o f + b l e e d i n g + b y + l i g a t u r e + o r + o t h e r + c o n v e n t i o n a l + m e t h o d s + i s + i n e f f e c t i v e + o r + i m p r a c t i c a l % 0 a % 0 d % 0 a % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a % 0 d % 0 a s t a t e m e n t s + m a d e + i n + t h i s + p r e s s + r e l e a s e + t h a t + l o o k + f o r w a r d + i n + t i m e + o r + t h a t + e x p r e s s + m a n a g e m e n t % 2 7 s + b e l i e f s % 2 c + e x p e c t a t i o n s + o r + h o p e s + a r e + f o r w a r d - l o o k i n g + s t a t e m e n t s + w i t h i n + t h e + m e a n i n g + o f + t h e + p r i v a t e + s e c u r i t i e s + l i t i g a t i o n + r e f o r m + a c t + o f + 1 9 9 5 + s u c h + f o r w a r d - l o o k i n g + s t a t e m e n t s + r e f l e c t + t h e + v i e w s + o f + m a n a g e m e n t + a t + t h e + t i m e + s u c h + s t a t e m e n t s + a r e + m a d e + a n d + a r e + s u b j e c t + t o + a + n u m b e r + o f + r i s k s % 2 c + u n c e r t a i n t i e s % 2 c + e s t i m a t e s % 2 c + a n d + a s s u m p t i o n s + t h a t + m a y + c a u s e + a c t u a l + r e s u l t s + t o + d i f f e r + m a t e r i a l l y + f r o m + c u r r e n t + e x p e c t a t i o n s + t h e s e + s t a t e m e n t s + i n c l u d e + t h o s e + r e g a r d i n g + t h e + % 2 4 2 5 0 % 2 b + m i l l i o n + w o r l d w i d e + m a r k e t + o p p o r t u n i t y + f o r + h e r o + g r a f t % 2 c + o u r + i n t e n t i o n + t o + u s e + c a s h + o n + h a n d + t o + f i n a n c e + t h e + t r a n s a c t i o n + w i t h + h e m o s p h e r e % 2 c + t h e + e x p e c t a t i o n + t h a t + t h e + t r a n s a c t i o n + w i l l + c l o s e + i n + m a y + 2 0 1 2 % 2 c + t h e + b e l i e f + t h a t + h e r o + g r a f t + w i l l + b e + a + h i g h e r + g r o w t h + a n d + h i g h e r + m a r g i n + p r o d u c t % 2 c + t h e + o p p o r t u n i t y + f o r + o u r + s a l e s + t e a m + t o + l e v e r a g e + t h e i r + r e l a t i o n s h i p s + w i t h + v a s c u l a r + s u r g e o n s + t o + e x p a n d + h e r o + g r a f t % 2 7 s + g e o g r a p h i c + a v a i l a b i l i t y + a n d + a c c e l e r a t e + i t s + g r o w t h + i n + t h e + u s % 2 c + i n c r e m e n t a l + h e r o + g r a f t + g r o w t h + o p p o r t u n i t i e s + r e p r e s e n t e d + b y + p o t e n t i a l + p r o d u c t + e n h a n c e m e n t s + a n d + i n t e r n a t i o n a l + s a l e s % 2 c + t h e + a d d i t i o n a l + g r o w t h + o p p o r t u n i t y + f o r + h e r o + g r a f t + o u t s i d e + t h e + u s + t h r o u g h + c r y o l i f e % 2 7 s + i n t e r n a t i o n a l + d i r e c t + a n d + d i s t r i b u t i o n + s a l e s + a n d + m a r k e t i n g + i n f r a s t r u c t u r e % 2 c + t h e + p r o d u c t % 2 7 s + e x p a n d i n g + r e i m b u r s e m e n t + r a t e s + i n + t h e + u s % 2 c + t h e + m e d i c a l + b e n e f i t s + a s s o c i a t e d + w i t h + h e r o + g r a f t % 2 c + i n c l u d i n g + t h e + r e d u c t i o n + o f + i n f e c t i o n s % 2 c + o u r + p l a n s % 2 c + e s t i m a t e d + t i m i n g + a n d + e x p e c t e d + b e n e f i t s + r e l a t e d + t o + t h e + i n t e g r a t i o n + o f + h e r o + g r a f t + s a l e s + i n t o + o u r + b u s i n e s s % 2 c + o u r + e s t i m a t e + t h a t + w e + w i l l + b e n e f i t + f r o m + t h e + a d d i t i o n + o f + h e m o s p h e r e % 2 7 s + e x i s t i n g + b u s i n e s s + t h i s + y e a r + a n d + b e g i n + d r i v i n g + a + m e a n i n g f u l + a c c e l e r a t i o n + o f + h e r o + g r a f t + g r o w t h + b e g i n n i n g + i n + 2 0 1 3 % 2 c + a n d + t h e + f i n a n c i a l + i m p a c t + o f + t h i s + t r a n s a c t i o n + o n + o u r + b u s i n e s s + t h e s e + r i s k s + a n d + u n c e r t a i n t i e s + i n c l u d e + t h a t + w e + m a y + n o t + b e + a b l e + t o + e f f e c t i v e l y + l e v e r a g e + o u r + e x i s t i n g + r e l a t i o n s h i p s + a n d + i n f r a s t r u c t u r e + t o + i n c r e a s e + h e r 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