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Bacteria-derived bile acids linked to efficacy of statins. |
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EurekAlert: Among the group who had a strong response to the drug, three bile acids appeared to play a role. The bile acids are produced by certain gut bacteria, which are increasingly understood as factories for chemicals that can contribute to a state of health. Among the people who responded poorly to the statin, five different bile acids were commonly evident. The researchers hypothesize that because bile acids and statins share transporter routes to the liver and intestines – they are basically in competition for a ride -- producing more or less of certain bile acids could improve or diminish the drug's effects.
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