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d i r e c t o r + o f + t h e + a n s a r y + s t e m + c e l l + i n s t i t u t e + a t + w e i l l + c o r n e l l + m e d i c a l + c o l l e g e + a n d + a + h o w a r d + h u g h e s + m e d i c a l + i n s t i t u t e + i n v e s t i g a t o r % 0 d % 0 a % 0 9 t h e + l i v e r + p e r f o r m s + m a n y + p h y s i o l o g i c a l + f u n c t i o n s % 2 c + i n c l u d i n g + c o n v e r t i n g + n u t r i e n t s + i n t o + e s s e n t i a l + b l o o d + c o m p o n e n t s % 3 b + s t o r i n g + v i t a m i n s + a n d + m i n e r a l s % 3 b + p r o d u c i n g + b i l e + f o r + d i g e s t i n g + f a t s % 3 b + r e g u l a t i n g + b l o o d + c l o t t i n g % 3 b + a n d + m e t a b o l i z i n g + a n d + d e t o x i f y i n g + s u b s t a n c e s + t h a t + w o u l d + o t h e r w i s e + b e + h a r m f u l + w h e n + t h e + l i v e r + m a l f u n c t i o n s % 2 c + t h e + c o n s e q u e n c e s + c a n + b e + g r a v e + l i v e r + f a i l u r e % 2 c + d u e + t o + c i r r h o s i s % 2 c + v a r i o u s + f o r m s + o f + h e p a t i t i s % 2 c + a n d + o t h e r + d i s e a s e s % 2 c + k i l l s + s o m e + 6 0 % 2 c 0 0 0 + a m e r i c a n s + p e r + y e a r + b u t + t h e + l i v e r % 2 7 s + c a p a c i t y + f o r + r e g e n e r a t i o n + i s + a m a z i n g % 0 d % 0 a % 0 9 % 2 2 u n t i l + o u r + s t u d y % 2 c + t h e + m o l e c u l a r + a n d + c e l l u l a r + p a t h w a y s + t h a t + w o u l d + i n i t i a t e + a n d + m a i n t a i n + l i v e r + r e g e n e r a t i o n + w e r e + n o t + k n o w n % 2 c % 2 2 + s a y s + d r + b i - s e n + d i n g % 2 c + t h e + s t u d y % 2 7 s + f i r s t + a u t h o r + a n d + a + s e n i o r + p o s t d o c t o r a l + f e l l o w + i n + d r + r a f i i % 2 7 s + l a b + % 2 2 a t t e m p t s + t o + t r a n s p l a n t + h e p a t o c y t e s + % 5 b l i v e r + c e l l s % 5 d + d i r e c t l y + i n t o + t h e + l i v e r + l e d + t o + v e r y + l i m i t e d + s u c c e s s + b u t + n o w + w e + h a v e + i d e n t i f i e d + l i v e r + s i n u s o i d a l + e n d o t h e l i a l + c e l l s + % 2 8 l s e c s % 2 9 + - - + t h a t % 2 c + w h e n + a c t i v a t e d % 2 c + a r e + c r i t i c a l + t o + l i v e r + r e g e n e r a t i o n + a n d + m a y + e n a b l e + p r o p e r + e n g r a f t m e n t + w h e n + h e p a t o c y t e s + a r e + i m p l a n t e d + i n t o + t h e + i n j u r e d + l i v e r % 2 2 % 0 d % 0 a % 0 9 d r + r a f i i % 2 7 s + t e a m + d e t e r m i n e d + t h e + m e c h a n i s m + b y + w h i c h + l s e c s + r e g u l a t e + l i v e r + r e g e n e r a t i o n + b y + s t u d y i n g + t h i s + p r o c e s s + i n + g e n e t i c a l l y + e n g i n e e r e d + m i c e + w h o s e + l i v e r s + w e r e + 7 0 + p e r c e n t + r e m o v e d + t h r o u g h + a + s e r i e s + o f + e x p e r i m e n t s + i n v o l v i n g + s t r a t e g i c + e n d o t h e l i a l + c e l l + i m p l a n t a t i o n % 2 c + t h e + t e a m + f o u n d + t h a t + o n l y + t h o s e + l s e c s + w h o s e + g e n e s + w e r e + p r o d u c i n g + t h e + a n g i o c r i n e + g r o w t h + f a c t o r s + i d 1 + o r + w n t 2 + a n d + % 2 2 h e p a t o c y t e + g r o w t h + f a c t o r % 2 2 + % 2 8 h g f % 2 9 + w o u l d + i n i t i a t e + a n d + s u s t a i n + l i v e r + r e g e n e r a t i o n + i t + i s + t h o u g h t + t h a t + w n t 2 + a n d + h g f + w o r k + t o g e t h e r + i n + i n i t i a t i n g + r e g e n e r a t i o n % 2 c + a n d + t h a t + t h e + l s e c s + a n d + t h e + l i v e r + c e l l s + m u s t + b e + n e x t + t o + e a c h + o t h e r + f o r + s u c c e s s f u l + r e g e n e r a t i o n + w e r e + k e y + f i n d i n g s + % 0 d % 0 a % 0 9 % 2 2 t h e r e f o r e % 2 c + t o + r e g e n e r a t e + a + l o n g - l a s t i n g + l i v e r % 2 c + w e + m a y + n e e d + t o + c o - t r a n s p l a n t + h e p a t o c y t e s + w i t h + t h e + p r o p e r l y + a c t i v a t e d + e n d o t h e l i u m % 2 c + w h i c h + p r o d u c e s + t h e + r i g h t + g r o w t h + f a c t o r s + f o r + t h e + h e p a t o c y t e s + t o + a t t a c h % 2 c + g r o w + a n d + c o n n e c t + w i t h + o t h e r + p a r t s + o f + t h e + l i v e r + c o - t r a n s p l a n t a t i o n + o f + p r i m e d + a c t i v a t e d + e n d o t h e l i u m + w i t h + l i v e r + c e l l s + m a y + b e + a n + i m p o r t a n t + s t e p + t o + d e s i g n + f u t u r e + t h e r a p i e s + t o + r e g e n e r a t e + t h e + l i v e r % 2 c % 2 2 + s a y s + d r + d i n g + % 0 d % 0 a % 0 9 d e s p i t e + t h e s e + n e w + i n s i g h t s % 2 c + d r + r a f i i + p o i n t s + t o + a n + u n s o l v e d + e n i g m a % 3 a + h o w + d o + e n d o t h e l i a l + c e l l s + s e n s e + t h e + l o s s + o f + l i v e r + t i s s u e + a n d + i n i t i a t e + t h e + r e g e n e r a t i o n + p r o c e s s % 3 f + % 2 2 c h a n g e + o f + b l o o d + f l o w + m i g h t + b e + o n e + o f + t h e + p o s s i b i l i t i e s % 2 c % 2 2 + s u g g e s t s + d r + s i n a + r a b b a n y % 2 c + s t u d y + c o - s e n i o r + a u t h o r % 2 c + w h o + i s + a n + a d j u n c t + p r o f e s s o r + a t + w e i l l + c o r n e l l + a n d + p r o f e s s o r + o f + b i o e n g i n e e r i n g + a t + h o f s t r a + u n i v e r s i t y + % 2 2 i t + i s + w e l l + k n o w n + t h a t + e n d o t h e l i a l + c e l l s + c a n + s e n s e + s u b t l e + c h a n g e s + i n + t h e + f l o w + o f + b l o o d + b e c a u s e + t h e y + a r e + l o c a t e d + a t + t h e + i n t e r f a c e + b e t w e e n + t h e + b l o o d + f l o w + a n d + v e s s e l + w a l l + t h e + l o s s + o f + a + l i v e r + l o b e + w i l l + i n e v i t a b l y + a l t e r + t h e + l o c a l + b l o o d + f l o w + p a t t e r n s + a n d + r e s u l t i n g + s h e a r + s t r e s s e s + t h a t + a r e + r e d i r e c t e d + i n t o + t h e + r e m a i n i n g + l o b e s + t h i s + a l t e r a t i o n + i n + t h e + b i o m e c h a n i c a l + t r a n s d u c t i o n + p r o c e s s + i s + p a r t + o f + a + c o m p l e x + s y s t e m + l i k e l y + t o + % 2 7 a c t i v a t e % 2 7 + e n d o t h e l i a l + c e l l s + t o + p r o d u c e + h e p a t o c y t e - a c t i v e + g r o w t h + f a c t o r s % 2 2 % 0 d % 0 a % 0 9 d r + d a v i d + l y d e n % 2 c + a + c o - a u t h o r + o n + t h e + p a p e r + a n d + t h e + s t a v r o s + n i a r c h o s + a s s o c i a t e + p r o f e s s o r + i n + p e d i a t r i c + c a r d i o l o g y + a t + w e i l l + c o r n e l l + m e d i c a l + c o l l e g e % 2 c + s a y s % 2 c + % 2 2 t h i s + i s + a n + i m p o r t a n t + s t u d y + b y + t a r g e t i n g + e n d o t h e l i a l - s p e c i f i c + g e n e s + s u c h + a s + i d 1 % 2 c + a s + i d e n t i f i e d + i n + t h i s + r e s e a r c h % 2 c + i + h o p e + t h a t + i t + w i l l + f a c i l i t a t e + t h e + d e s i g n + o f + n e w + t h e r a p i e s + t o + t r e a t + p e o p l e + w i t h + l i v e r + d i s e a s e % 2 c + w h e t h e r + d u e + t o + i n f e c t i o n % 2 c + c a n c e r % 2 c + o r + a c u t e + o r + l o n g - t e r m + d a m a g e % 2 2 % 0 d % 0 a % 0 9 e a r l i e r + t h i s + y e a r % 2 c + r a f i i % 2 7 s + t e a m + d e v e l o p e d + a + n e w + t e c h n i q u e + a n d + d e s c r i b e d + a + n o v e l + m e c h a n i s m + f o r + t u r n i n g + h u m a n + e m b r y o n i c + a n d + p l u r i p o t e n t + s t e m + c e l l s + i n t o + p l e n t i f u l % 2 c + f u n c t i o n a l + e n d o t h e l i a l + c e l l s % 2 c + w h i c h + a r e + c r i t i c a l + t o + t h e + f o r m a t i o n + o f + b l o o d + v e s s e l s + t h e + n e w + a p p r o a c h + a l l o w s + s c i e n t i s t s + t o + g e n e r a t e + v i r t u a l l y + u n l i m i t e d + q u a n t i t i e s + o f + d u r a b l e + e n d o t h e l i a l + c e l l s + - - + m o r e + t h a n + 4 0 - f o l d + t h e + q u a n t i t y + p o s s i b l e + w i t h + p r e v i o u s + a p p r o a c h e s + % 2 2 t h e s e + e m b r y o n i c - d e r i v e d + e n d o t h e l i a l + c e l l s + m a y + p r o v i d e + a + u s e f u l + p l a t f o r m + t o + e x p a n d + l i v e r + a n d + b l o o d + s t e m + c e l l s + f o r + t h e r a p e u t i c + t r a n s p l a n t a t i o n % 2 c % 2 2 + s t a t e s + d r + z e v + r o s e n w a k s % 2 c + w h o + i s + a + c o - a u t h o r + i n + t h i s + s t u d y + a n d + d i r e c t o r + a n d + p h y s i c i a n - i n - c h i e f + o f + t h e + r o n a l d + o + p e r e l m a n + a n d + c l a u d i a + c o h e n + c e n t e r + f o r + r e p r o d u c t i v e + m e d i c i n e % 2 c + a s + w e l l + a s + t h e + d i r e c t o r + o f + t h e + t r i - i n s t i t u t i o n a l + s t e m + c e l l + i n i t i a t i v e + d e r i v a t i o n + u n i t + a t + w e i l l + c o r n e l l + m e d i c a l + c o l l e g e % 0 d % 0 a % 0 9 % 2 2 o n e + o f + t h e + m o s t + r e m a r k a b l e + f i n d i n g s + o f + o u r + s t u d i e s + i s + t h e + r e a l i z a t i o n + t h a t + e n d o t h e l i a l + c e l l s + w i t h i n + e a c h + o r g a n + a r e + f u n c t i o n a l l y + d i f f e r e n t % 2 c + a n d + o n c e + a c t i v a t e d + p r o d u c e + a + u n i q u e + s e t + o f + g r o w t h + f a c t o r s % 2 c % 2 2 + s t a t e s + d r + r a f i i + % 2 2 t h e + c h a l l e n g e + t h a t + l i e s + a h e a d + i s + t o + d i s c o v e r + t h e + o r g a n - s p e c i f i c + g r o w t h + f a c t o r s + p r o d u c e d + b y + t h e + e n d o t h e l i a l + c e l l s + t h a t + i n i t i a t e + t h e + r e g e n e r a t i o n + o f + t h a t + p a r t i c u l a r + o r g a n + t h e n % 2 c + t h e s e + f a c t o r s + c o u l d + b e + e x p l o i t e d + t h e r a p e u t i c a l l y + t o + i n d u c e + s e l e c t i v e + r e g e n e r a t i o n + o f + o n e + o r g a n + w i t h o u t + a f f e c t i n g + o t h e r s % 2 2 + % 0 d % 0 a % 0 9 a d d i t i o n a l + c o - a u t h o r s + i n c l u d e + d a n i e l + j + n o l a n % 2 c + j a s o n + m + b u t l e r % 2 c + d a y l o n + j a m e s % 2 c + a l e x a n d e r + o + b a b a z a d e h + a n d + k o j i + s h i d o % 2 c + a l l + o f + t h e + a n s a r y + s t e m + c e l l + i n s t i t u t e + i n + t h e + d e p a r t m e n t + o f + g e n e t i c + m e d i c i n e % 2 c + w e i l l + c o r n e l l + m e d i c a l + c o l l e g e % 2 c + a n d + t h e + h o w a r d + h u g h e s + m e d i c a l + i n s t i t u t e % 3 b + d r + v i v e k + m i t t a l % 2 c + d e p a r t m e n t + o f + s u r g e r y % 2 c + w e i l l + c o r n e l l + m e d i c a l + c o l l e g e % 3 b + a n d + d r + t h o m a s + n + s a t o % 2 c + g r a d u a t e + s c h o o l + o f + b i o l o g i c a l + s c i e n c e s % 2 c + n a r a + i n s t i t u t e + o f + s c i e n c e + a n d + t e c h n o l o g y % 2 c + n a r a % 2 c + j a p a n % 0 d % 0 a % 0 9 h o w + v a s c u l a r + e n d o t h e l i a l + c e l l s + r e n e w + b l o o d + s t e m + c e l l s + a n d + c o n t r o l + s t e m + c e l l s % 2 7 + d i f f e r e n t i a t i o n % 0 d % 0 a % 0 9 a n o t h e r + s t u d y + b y + t h e + s a m e + g r o u p % 2 c + p u b l i s h e d + i n + t h e + o c t + 2 4 + i s s u e + o f + n a t u r e + c e l l + b i o l o g y % 2 c + e x a m i n e s + h o w + a + s i m i l a r + t y p e + o f + s i n u s o i d a l + e n d o t h e l i a l + c e l l s + t h a t + p r o m o t e + l i v e r + r e g e n e r a t i o n + a l s o + a r e + a c t i v a t e d + t o + r e n e w + b l o o d + s t e m + c e l l s + a n d + c o n t r o l + t h e i r + d i f f e r e n t i a t i o n + i n t o + v a r i o u s + t y p e s + o f + b l o o d + c e l l s + w i t h i n + t h e + b o n e + m a r r o w + t h e + f i n d i n g s + m a y + b e + u s e d + t o + c r e a t e + m a s s + q u a n t i t i e s + o f + s t e m + c e l l s + f o l l o w i n g + t r a u m a + t o + t h e + b o n e + m a r r o w % 2 7 s + m i c r o e n v i r o n m e n t % 0 d % 0 a % 0 9 f o l l o w i n g + i n j u r y + f r o m + t h e r a p e u t i c + r a d i a t i o n + o r + c h e m o t h e r a p y % 2 c + s t e m + c e l l s + i n + t h e + b o n e + m a r r o w + a r e + i n j u r e d % 2 c + h a m p e r i n g + b l o o d + c e l l + p r o d u c t i o n + s o m e + p a t i e n t s + e x p e r i e n c e + s e v e r e + a n d + p o t e n t i a l l y + i r r e v e r s i b l e + t r a u m a + t o + t h e i r + a b i l i t y + t o + p r o d u c e + b l o o d + c e l l s + u n t i l + n o w + i t + h a s + b e e n + u n c l e a r + h o w + t h e + b o d y + s i g n a l s + t h e s e + s t e m + c e l l s + t o + r e g e n e r a t e + a n d + t o + d i f f e r e n t i a t e + i n t o + c e l l s + t h a t + f o r m + b l o o d + c e l l s + % 0 d % 0 a % 0 9 d r + r a f i i + a n d + h i s + l a b + h a v e + s h o w n + t h a t + e n d o t h e l i a l + c e l l s + r e l e a s e + s p e c i f i c + a n g i o c r i n e + g r o w t h + f a c t o r s + i n t o + t h e + e n v i r o n m e n t + o f + t h e + b o n e + m a r r o w % 2 c + t e l l i n g + t h e + b o d y + t o + p r o d u c e + m o r e + s t e m + c e l l s + t h e + r e s e a r c h e r s + s h o w e d + t h a t + t h e + a k t - p a t h w a y + i s + a c t i v a t e d + i n + t h e + e n d o t h e l i a l + c e l l s % 2 c + w h i c h + t u r n s + o n + e x p r e s s i o n + o f + a + g r o u p + o f + g r o w t h + f a c t o r s + t h a t + i n d u c e s + t h e + b o n e + m a r r o w + t o + p r o d u c e + m o r e + s t e m + c e l l s + f o l l o w i n g + t h e + a c t i v a t i o n + o f + t h e + a k t - p a t h w a y % 2 c + t h e + m a p + k i n a s e + p a t h w a y + i s + a c t i v a t e d % 2 c + w h i c h + s t i m u l a t e s + t h e + p r o d u c t i o n + o f + a n g i o c r i n e + f a c t o r s + t h a t + c o n t r o l + t h e + d i f f e r e n t i a t i o n + o f + t h e + s t e m + c e l l s + i n t o + v a r i o u s + c e l l s + n e e d e d + t o + m a k e + u p + b l o o d + % 0 d % 0 a % 0 9 r e s u l t s + f r o m + t h e + s t u d y + s h o w + a + 1 0 - f o l d + i n c r e a s e + o f + s t e m + c e l l + p r o d u c t i o n + i n + m o u s e + m o d e l s + t h a t + e x p r e s s + h i g h e r + l e v e l s + o f + a k t + s e l e c t i v e l y + i n + e n d o t h e l i a l + c e l l s % 2 c + w h e n + c o m p a r e d + w i t h + c o n t r o l + m i c e + i f + p r o v e n + a p p l i c a b l e + i n + h u m a n s % 2 c + t h e + f i n d i n g s + m a y + l e a d + t o + a + n e w + w a y + o f + t r e a t i n g + p a t i e n t s + s u f f e r i n g + f r o m + b o n e + m a r r o w + d e f i c i e n c i e s + % 0 d % 0 a % 0 9 % 2 2 y o u + a r e + e s s e n t i a l l y + c r e a t i n g + a + c e l l + c u l t u r e + b i o r e a c t o r + c a p a b l e + o f + p r o d u c i n g + l a r g e + n u m b e r s + o f + s t e m + c e l l s + a s + w e l l + a s + m a t u r e + b l o o d + c e l l s % 2 c + w h i c h + c a n + r e s t o r e + b o n e + m a r r o w + f o l l o w i n g + t r a u m a % 2 c % 2 2 + s a y s + d r + j a s o n + b u t l e r % 2 c + w h o + a l o n g + w i t h + d r + h i d e k i + k o b a y a s h i + i s + t h e + s t u d y % 2 7 s + c o - f i r s t + a u t h o r + a n d + s e n i o r + p o s t d o c t o r a l + f e l l o w s + i n + d r + r a f i i % 2 7 s + l a b + % 0 d % 0 a % 0 9 % 2 2 u s i n g + p r o p e r l y + a c t i v a t e d + o r g a n - s p e c i f i c + e n d o t h e l i a l + c e l l s + t o + p r o p a g a t e + e n o u g h + s t e m + a n d + p r o g e n i t o r + c e l l s % 2 c + s u c h + a s + t h o s e + o f + b o n e + m a r r o w + a n d + l i v e r % 2 c + s o + t h e y + c a n + b e + u s e d + c l i n i c a l l y + h a s + b r o a d + t h e r a p e u t i c + i m p l i c a t i o n s + n o t + o n l y + f o r + r e g e n e r a t i v e + m e d i c i n e % 2 c + b u t + a l s o + f o r + t h e + s t u d y + o f + g e n e t i c + d i s e a s e s % 2 c % 2 2 + c o n c l u d e s + d r + r a f i i + % 0 d % 0 a % 0 d % 0 a % 0 9 a d d i t i o n a l + c o - a u t h o r s + i n c l u d e + m a r i k o + k o b a y a s h i % 2 c + b i - s e n + d i n g % 2 c + b r y a n t + b o n n e r % 2 c + v i + c h i u % 2 c + d a n i e l + n o l a n % 2 c + k o j i + s h i d o % 2 c + a l l + f r o m + w e i l l + c o r n e l l % 3 b + a n d + l a u r a + b e n j a m i n + a n d + r e b e k a h + o % 2 7 d o n n e l l % 2 c + f r o m + t h e + b e t h + i s r a e l + d e a c o n e s s + m e d i c a l + c e n t e r % 2 c + h a r v a r d + m e d i c a l + s c h o o l % 2 c + b o s t o n % 2 c + m a s s % 0 d % 0 a % 0 9 % 0 9 t h e + n a t u r e + a n d + n a t u r e + c e l l + b i o l o g y + s t u d i e s + w e r e + b o t h + s u p p o r t e d + b y + g r a n t s + f r o m + t h e + h o w a r d + h u g h e s + m e d i c a l + i n s t i t u t e % 2 c + t h e + a n s a r y + s t e m + c e l l + i n s t i t u t e % 2 c + t h e + n a t i o n a l + i n s t i t u t e s + o f + h e a l t h % 2 c + q a t a r + n a t i o n a l + p r i o r i t i e s + r e s e a r c h + p r o g r a m % 2 c + t h e + a n b i n d e r + f o u n d a t i o n % 2 c + n e w m a n % 2 7 s + o w n + f o u n d a t i o n % 2 c + t h e + e m p i r e + s t a t e + s t e m + c e l l + b o a r d % 2 c + a n d + t h e + n e w + y o r k + s t a t e + d e p a r t m e n t + o f + h e a l t h % 0 d % 0 a % 0 9 t h e + a n s a r y + s t e m + c e l l + i n s t i t u t e % 0 d % 0 a % 0 9 t h e + a n s a r y + s t e m + c e l l + i n s t i t u t e + b r i n g s + t o g e t h e r + a + p r e m i e r + t e a m + o f + s c i e n t i s t s + t o + f o c u s + o n + s t e m + c e l l s % 2 c + w h i c h + a r e + i m m a t u r e % 2 c + u n s p e c i a l i z e d + c e l l s + w i t h + t h e + c a p a c i t y + t o + f o r m + a l l + t y p e s + o f + c e l l s % 2 c + t i s s u e s + a n d + o r g a n s + i n + t h e + b o d y + t h e + a n s a r y + i n s t i t u t e + t a k e s + a + c o l l a b o r a t i v e + a p p r o a c h + t o + s t e m + c e l l + r e s e a r c h + b y + b r i n g i n g + t o g e t h e r + s c i e n t i s t s + f r o m + v a r i e d + a r e a s + o f + b i o m e d i c a l + r e s e a r c h + t h e + i n s t i t u t e + w a s + e s t a b l i s h e d + i n + 2 0 0 4 + w i t h + a + g e n e r o u s + g i f t + f r o m + m r + h u s h a n g + a n s a r y + s i n c e + t h e n % 2 c + t h e + i n s t i t u t e + g a r n e r e d + a p p r o x i m a t e l y + % 2 4 2 6 + m i l l i o n + i n + e x t e r n a l + f u n d i n g % 2 c + i n c l u d i n g + s u p p o r t + f r o m + t h e + s t a r r + f o u n d a t i o n + t r i - i n s t i t u t i o n a l + s t e m + c e l l + i n i t i a t i v e + a n d + t h e + e m p i r e + s t a t e + s t e m + c e l l + b o a r d + % 2 8 n y s t e m % 2 9 + a n s a r y + i n s t i t u t e + r e s e a r c h e r s + h a v e + m a d e + g r o u n d b r e a k i n g + d i s c o v e r i e s + t h a t + s h o w + s i g n i f i c a n t + p r o m i s e + f o r + t h e + f u t u r e + o f + r e g e n e r a t i v e + m e d i c i n e + % 2 8 m a r s h a l l i n g + t h e + b o d y % 2 7 s + o w n + r e s o u r c e s + t o + r e s t o r e + i t s e l f % 2 9 % 2 c + t h e + t r e a t m e n t + o f + c a r d i o v a s c u l a r + d i s e a s e % 2 c + a n d + m o r e + r e c e n t + n o t a b l e + a n s a r y + i n s t i t u t e + d i s c o v e r i e s + i n c l u d e + c l e a r + s t e p s + t o w a r d + t h e + e v e n t u a l + c l i n i c a l + a p p l i c a b i l i t y + o f + s t e m + c e l l s % 3 a + i d e n t i f y i n g + i n + a d u l t + m o u s e + t e s t e s + c e l l s + t h a t + c a n + b e + c o n v e r t e d + t o + s t e m + c e l l s + t h a t + i n + t u r n + g e n e r a t e + c a r d i a c % 2 c + v a s c u l a r + a n d + n e u r o n a l + c e l l + t y p e s % 3 b + t h e + u n l i m i t e d + e x p a n s i o n + o f + b l o o d - p r o d u c i n g + s t e m + c e l l + c u l t u r e s % 2 c + w h e r e a s + p r e v i o u s + b e s t + e f f o r t s + w o u l d + r e s u l t + i n + a + c o l o n y + o f + s t e m + c e l l s + d y i n g + a f t e r + a + f e w + d a y s % 3 b + a n d + t h e + u n l i m i t e d + g e n e r a t i o n + o f + e n d o t h e l i a l + c e l l s + % 2 8 t h e + b a s i c + b u i l d i n g + b l o c k s + o f + t h e + c i r c u l a t o r y + s y s t e m % 2 9 + f r o m + h u m a n + e m b r y o n i c + s t e m + c e l l s + t h e + a n s a r y + i n s t i t u t e + i n t e n d s + t o + l e a d + t h e + w a y + i n + s t e m + c e l l + s c i e n c e + t o + r e l i e v e + h u m a n + s u f f e r i n g % 0 d % 0 a % 0 9 w e i l l + c o r n e l l + m e d i c a l + c o l l e g e + % 0 d % 0 a % 0 9 w e i l l + c o r n e l l + m e d i c a l + c o l l e g e % 2 c + c o r n e l l + u n i v e r s i t y % 2 7 s + m e d i c a l + s c h o o l + l o c a t e d + i n + n e w + y o r k + c i t y % 2 c + i s + c o m m i t t e d + t o + e x c e l l e n c e + i n + r e s e a r c h % 2 c + t e a c h i n g % 2 c + p a t i e n t + c a r e + a n d + t h e + a d v a n c e m e n t + o f + t h e + a r t + a n d + s c i e n c e + o f + m e d i c i n e % 2 c + l o c a l l y % 2 c + n a t i o n a l l y + a n d + g l o b a l l y + p h y s i c i a n s + a n d + s c i e n t i s t s + o f + w e i l l + c o r n e l l + m e d i c a l + c o l l e g e + a r e + e n g a g e d + i n + c u t t i n g - e d g e + r e s e a r c h + f r o m + b e n c h + t o + b e d s i d e % 2 c + a i m e d + a t + u n l o c k i n g + m y s t e r i e s + o f + t h e + h u m a n + b o d y + i n + h e a l t h + a n d + s i c k n e s s + a n d + t o w a r d + d e v e l o p i n g + n e w + t r e a t m e n t s + a n d + p r e v e n t i o n + s t r a t e g i e s + i n + i t s + c o m m i t m e n t + t o + g l o b a l + h e a l t h + a n d + e d u c a t i o n % 2 c + w e i l l + c o r n e l l + h a s + a + s t r o n g + p r e s e n c e + i n + p l a c e s + s u c h + a s + q a t a r % 2 c + t a n z a n i a % 2 c + h a i t i % 2 c + b r a z i l % 2 c + a u s t r i a + a n d + t u r k e y + t h r o u g h + t h e + h i s t o r i c + w e i l l + c o r n e l l + m e d i c a l + c o l l e g e + i n + q a t a r % 2 c + t h e + m e d i c a l + c o l l e g e + i s + t h e + f i r s t + i n + t h e + u s + t o + o f f e r + i t s + m d + d e g r e e + o v e r s e a s + w e i l l + c o r n e l l + i s + t h e + b i r t h p l a c e + o f + m a n y + m e d i c a l + a d v a n c e s + - - + i n c l u d i n g + t h e + d e v e l o p m e n t + o f + t h e + p a p + t e s t + f o r + c e r v i c a l + c a n c e r % 2 c + t h e + s y n t h e s i s + o f + p e n i c i l l i n % 2 c + t h e + f i r s t + s u c c e s s f u l + e m b r y o - b i o p s y + p r e g n a n c y + a n d + b i r t h + i n + t h e + u s % 2 c + t h e + f i r s t + c l i n i c a l + t r i a l + o f + g e n e + t h e r a p y + f o r + p a r k i n s o n % 2 7 s + d i s e a s e % 2 c + a n d + m o s t + r e c e n t l y % 2 c + t h e + w o r l d % 2 7 s + f i r s t + s u c c e s s f u l + u s e + o f + d e e p + b r a i n + s t i m u l a t i o n + t o + t r e a t + a + m i n i m a l l y + c o n s c i o u s + b r a i n - i n j u r e d + p a t i e n t + w e i l l + c o r n e l l + m e d i c a l + c o l l e g e + i s + a f f i l i a t e d + w i t h + n e w y o r k - p r e s b y t e r i a n + h o s p i t a l % 2 c + w h e r e + i t s + f a c u l t y + p r o v i d e s + c o m p r e h e n s i v e + p a t i e n t + c a r e + a t + n e w y o r k - 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